![]() ![]() If the mean platelet volume is elevated, it means that the platelet is large and more reactive. Mean platelet volume measures how reactive and large the platelets are. ![]() Giving aspirin could further lead to bleeding. Hence, a person with low mean platelet should completely avoid aspirin. A low mean platelet volume can put you at risk for bleeding because the clotting factor of the blood is impaired.To prevent the blood from clumping, doctors usually prescribe aspirin. Since there is excessive production of platelet, there is a tendency that the blood will clump together, which puts the patient at risk for thrombosis, cardiovascular diseases, and stroke. Blood clumping is common in people with high mean platelet volume.These drugs are toxic to the cells and they should be used in moderation. A low MPV can be caused by a certain types of drugs.A high MPV and high platelet count indicates that the bone marrow is producing too much platelets.It could also indicate hyperthyroidism (over production of thyroid hormones). If the platelet count is normal but the mean platelet volume is high, it could indicate chronic myeloid leukemia (over production of a specific type of white blood cells).This is common in patients with immune thrombocytopenia and pre-eclampsia. If the platelet count is low but the mean platelet volume is high, it indicates that there is a destruction in platelet.Purplish spots and rashes are also the reasons for PDW monitoring. It is also checked in patients with several episodes of nose bleeding. The doctor will thoroughly check PDW if the patient is suffering from unexplained bruising and excessive bleeding from small wounds and cuts. Platelet Distribution Width is a part of CBC (Complete Blood Count). If the number of large platelets is high in a patient with a low platelet count, it is an indicator that the bone marrow is now producing sufficient level of platelets. Smaller platelets have been around for several days. Ideally, younger platelets are large in size. It is significant in determining the functions of the bone marrow. It measures the platelet’s uniformity in size. PDW stands for Platelet Distribution Width. Please note : Immature platelet fraction normal range and its uses ![]() It will be extremely difficult for the body to clot the blood during bleeding because of inadequate amount of platelet. Patients suffering from thrombocytopenia are prone to bleeding.
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